If you’re curious about how cannabis topicals actually work—or how your body is wired to interact with cannabinoids—you’re not alone. The science is still evolving, but there’s a growing body of research and education out there. Here are some trusted resources to get you started:
🎥 Watch: What Is the Endocannabinoid System?
“What Is the Endocannabinoid System?” (YouTube, 3 min)
A clear and beginner-friendly video explaining how the ECS helps regulate inflammation, mood, immune function, and more—and why cannabinoids interact with it.
📚 Read: Scientific Papers & Reviews
Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System (Molecules, 2019)
A deeper dive into how cannabinoids may support skin health, barrier function, and immune balance—highlighting the potential of topical formulations for dermatological use.
Cannabinoids in Dermatology: A Scoping Review (Dermatology Online Journal, 2018)
A broad look at how cannabinoids like CBD are being studied for acne, psoriasis, dermatitis, and wound healing. Promising early evidence, though more clinical research is needed.
Cannabinoids for the treatment of autoimmune and inflammatory skin diseases: A systematic review. (Experimental Dermatology, 2023)
Cannabinoids may benefit inflammatory skin conditions by acting on the skin’s endocannabinoid system.
The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities. (Trends, 2009)
The skin has its own endocannabinoid system (ECS)…and when disrupted, may contribute to skin conditions like acne, dermatitis, psoriasis, and pain.
🧭 Explore More: #HealthyNotHigh Blog Series
Curious about the difference between full-spectrum and isolate? Want to know how the entourage effect works or why we don’t use synthetic emulsifiers?
Check out our blog series where we break it all down, simply and honestly.
